AHC (Academic Health Center) Faculty Research Development Grant Funding:
- Dr. Barry Finzel received $167,000 for his project, "Bivalent conjugates for Inhibition of CD44."
- Dr. Philip Portoghese received $193,078 for his project, "Developing new therapies for neuropathic pain during multiple sclerosis."
- Dr. Natalia Tretyakova received $200,000 for her project, "UHRF2 control of 5hmC homeostasis and differentiation in retinal progenitor cells."
National Cancer Institute (NCI) Grant Funding:
- Dr. Natalia Tretyakova is part of a group that received NCI funding for the project, "Mechanisms of Ethnic/Racial Differences in Lung Cancer Due to Cigarette Smoking." The principal investigator is Dr. Steven Hecht and the project involves the U of M, the U of Hawaii and ESC.
National Institutes of Health (NIH) Funding:
- Jon Hawkinson, Director of the ITDD Highthrougput Screening Laboratory, received an NIH shared instrumentation award in the amount of $343,887. The plasmon resonance (SPR) instrument will allow researchers at the University of Minnesota to directly determine the affinity of antibodies and small molecule probes and drugs for receptors, and to measure protein-protein interactions. The exquisite sensitivity of this SPR instrument will allow the detection of very small mass changes in small molecule drug discovery applications, such as fragment-based screening. This instrument will directly impact research in diverse therapeutic areas, including contraception, anti-infectives, metabolic disease, neuroscience, and cancer, as well as basic biology research.
